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Physical Medicine and Rehabilitation Research at the ϰϲͼ

Matt Durand, PhDThe PM&R Research Program exists to advance the science and practice of physical medicine and rehabilitation. Our program aims to better understand and reduce impairments and functional disabilities due to disease or traumatic events. We cover a wide spectrum of research in our Program, including community engagement, clinical and translational research, quality improvement, and medical and resident education. Clinicians and researchers in PM&R conduct industry sponsored clinical trials, grant-supported investigator initiated clinical studies, and departmentally supported clinical studies (retrospective and prospective) that significantly contribute to improving clinical practice and patient care.

Research in our PM&R Department is highly diverse and collaborative. Our current research areas of interest include spinal cord injury, health improvements through physical activity, stroke rehabilitation, spasticity management, pain, prehabilitation, vascular biology, and prosthetics. Current collaborators include ϰϲͼ faculty in other clinical and basic science departments, as well as extensive collaborations with the Departments of Physical Therapy and Biomedical Engineering at Marquette University and the College of Health Sciences at the University of Wisconsin – Milwaukee. PM&R at ϰϲͼ also has an excellent research partner in the Clement J. Zablocki VA Medical Center. Our community partners include the Wisconsin Adaptive Sports Association and the Stroke Rehabilitation Center Community Academic Advisory Board, among others.

Our Residency Program includes a research requirement. Our unique Research-Intensive Track offers protected research time, funding, and significant mentorship opportunities for residents who have career goals that include conducting clinical research. Our trainees routinely present their work at national meetings, including, but not limited to, the annual meetings of the American Academy of Physical Medicine and Rehabilitation, Association of Academic Psychiatrists, and American Medical Society for Sports Medicine. Our residents also have had their research projects independently funded by associations like the Foundation for Physical Medicine and Rehabilitation as well as the United States Department of Veterans Affairs. Please visit the Residency Program page for more information on resident research.

Pictured: Matt Durand, PhD, Research Director

The Stroke Rehabilitation Center of Southeastern Wisconsin

Our partnership with Marquette University has established The Stroke Rehabilitation Center of Southeastern Wisconsin (SRC). The goal of this center is to conduct cutting edge rehabilitation research to improve functional outcomes for stroke survivors. Our research in this area is guided by a Community Academic Advisory Board comprised of clinicians, stroke survivors, caregivers, and academic researchers. Please to learn more.

View the 2019 SRC Annual Report (PDF)

Publications

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2021

Choi H, Varghese V, Baisden J, Braza DW, Banerjee A, Yoganandan N. . Mil Med. 2021 Jan 25;186(Suppl 1):632-638. doi: 10.1093/milmed/usaa433. PMID: 33499469.

Francisco GE, Balbert A, Bavikatte G, Bensmail D, Carda S, Deltombe T, Draulans N, Escaldi S, Gross R, Jacinto J, Ketchum N, Molteni F, Moraleda S, ODell MW, Reebye R, Säterö P, Verduzco-Gutierrez M, Walker H, Wissel J. . J Rehabil Med. 2021 Jan 1;53(1):jrm00134. doi: 10.2340/16501977-2753. PMID: 33057730.

Bosques G, Ankam NS, Kasi R, Rydberg L, Sauter C, Therattil M, Tolchin DW. . Am J Phys Med Rehabil. 2021 Feb 19. doi: 10.1097/PHM.0000000000001703. Epub ahead of print. PMID: 33496438.

2020

Jozwiak MJ, Wu H. . Pain Pract. 2020 Jan;20(1):88-94. doi: 10.1111/papr.12825. Epub 2019 Sep 12. PMID: 31357254.

Donohue NK, Graf EJ, Visotcky AM, Tarima SS, Hsu AC (2020) . Int J Physiatry 6:019. doi.org/10.23937/2572-4215.1510019 Jan 2020

Baer HR, Gilbert AR, Forster JE, Ketchum NC, Mallow M, Nguyen VQC. . Am J Phys Med Rehabil. 2020 Jan;99(1):81-85. doi: 10.1097/PHM.0000000000001302. PMID: 31464758.

Patel JJ, Baruah D, Sobush D, Koester K, Aase J, Zellner S, Graf J, Durand MJ, Szabo A, Shahir K. . Nutr Clin Pract. 2020 Feb;35(1):133-141. doi: 10.1002/ncp.10325. Epub 2019 Jun 6. PMID: 31172570.

Donohue NK, Tarima SS, Durand MJ, Wu H. . Korean J Pain. 2020 Apr 1;33(2):192-198. doi: 10.3344/kjp.2020.33.2.192. PMID: 32235020; PMCID: PMC7136301.

Janarthanan V, Assad-Uz-Zaman M, Rahman MH, McGonigle E, Wang I. . J Hand Ther. 2020 Apr-Jun;33(2):209-219. doi: 10.1016/j.jht.2020.03.023. Epub 2020 May 23. PMID: 32451172.

Cyr AK, Colorado BS, Uihlein MJ, Garlanger KL, Tarima SS, Lee K. . J Spinal Cord Med. 2020 Jun 12:1-7. doi: 10.1080/10790268.2020.1771243. Epub ahead of print. PMID: 32527209.

Iverson M, Ng AV, Yan AF, Zvara K, Bonk M, Falk-Palec D, Sylla C, Strickland M, Preston R, Braza DW. . Am J Phys Med Rehabil. 2020 Jul 15. doi: 10.1097/PHM.0000000000001533. Epub ahead of print. PMID: 32675707.

Assad Uz Zaman, M., Islam, M.R., Rahman, M.H. et al. . Multimed Tools Appl 79, 26643–26660 (2020). https://doi.org/10.1007/s11042-020-09266-x

Sotelo MR, Kalinosky BT, Goodfriend K, Hyngstrom AS, Schmit BD. . Brain Connect. 2020 Oct;10(8):399-410. doi: 10.1089/brain.2019.0725. Epub 2020 Sep 24. PMID: 32731752.

Durand MJ, Hader SN, Derayunan A, Zinkevich N, McIntosh JJ, Beyer AM. . Microcirculation. 2020 Oct;27(7):e12625. doi: 10.1111/micc.12625. Epub 2020 Sep 5. PMID: 32395853; PMCID: PMC7606774.

Harper MW, Lee J, Sherman KA, Uihlein MJ, Lee KKK. . Am J Phys Med Rehabil. 2020 Oct 22. doi: 10.1097/PHM.0000000000001630. Epub ahead of print. PMID: 33105155.

Hyngstrom AS, Nguyen JN, Wright MT, Tarima SS, Schmit BD, Gutterman DD, Durand MJ. . J Appl Physiol (1985). 2020 Dec 1;129(6):1348-1354. doi: 10.1152/japplphysiol.00398.2020. Epub 2020 Oct 22. PMID: 33090908; PMCID: PMC7792845.

2019

Durand MJ, Boerger TF, Nguyen JN, Alqahtani SZ, Wright MT, Schmit BD, Gutterman DD, Hyngstrom AS. . J Appl Physiol (1985). 2019 Mar 1;126(3):755-763. doi: 10.1152/japplphysiol.00772.2018. Epub 2019 Jan 17. PMID: 30653420; PMCID: PMC6459385.

Murphy S, Durand M, Negro F, Farina D, Hunter S, Schmit B, Gutterman D, Hyngstrom A. . Front Physiol. 2019 May 10;10:545. doi: 10.3389/fphys.2019.00545. PMID: 31133877; PMCID: PMC6524339.

Durand MJ, Ait-Aissa K, Levchenko V, Staruschenko A, Gutterman DD, Beyer AM. . Cardiovasc Res. 2019 Aug 1;115(10):1546-1556. doi: 10.1093/cvr/cvy294. PMID: 30476208; PMCID: PMC6648341.

Nelson MES, McGuire JR. . Neuromodulation. 2019 Oct;22(7):839-842. doi: 10.1111/ner.12974. Epub 2019 Jun 3. PMID: 31157471.

Durand, M.J., Beckert, A.K., Peterson, C.Y. et al. . Curr Anesthesiol Rep 9, 380–386 (2019). https://doi.org/10.1007/s40140-019-00357-6

Forseth B, Papanek PE, Bandini L, Schoeller D, Moosreiner A, Sawin KJ, Zvara K, Fendrich M, Polfuss M. . Compr Child Adolesc Nurs. 2019 Dec;42(4):293-303. doi: 10.1080/24694193.2019.1606864. Epub 2019 Jun 14. PMID: 31199888; PMCID: PMC6915061.

Nelson MES, Orr M. . An evidenced-based systematic review of the literature. J Spinal Cord Med. 2019 Dec 6:1-8. doi: 10.1080/10790268.2019.1696077. Epub ahead of print. PMID: 31809250.

2018

Kadlec AO, Barnes C, Durand MJ, Gutterman DD. . Am J Hypertens. 2018 Jan 12;31(2):240-246. doi: 10.1093/ajh/hpx162. PMID: 29140431; PMCID: PMC5861535.

Liu XC, Embrey D, Tassone C, Zvara K, Brandsma B, Lyon R, Goodfriend K, Tarima S, Thometz J. . PM R. 2018 Mar;10(3):269-275. doi: 10.1016/j.pmrj.2017.08.438. Epub 2017 Sep 1. PMID: 28867667.

Kim W, Lee L, Lans D, Tostenrude D, Lee K. . PM R. 2018 Mar;10(3):263-268. doi: 10.1016/j.pmrj.2017.09.002. Epub 2017 Sep 20. PMID: 28939461.

Liu XC, Embrey D, Tassone C, Zvara K, Brandsma B, Lyon R, Goodfriend K, Tarima S, Thometz J. . PM R. 2018 Mar;10(3):269-275. doi: 10.1016/j.pmrj.2017.08.438. Epub 2017 Sep 1. PMID: 28867667.

Ma C, Beyer AM, Durand M, Clough AV, Zhu D, Norwood Toro L, Terashvili M, Ebben JD, Hill RB, Audi SH, Medhora M, Jacobs ER. . Arterioscler Thromb Vasc Biol. 2018 Mar;38(3):622-635. doi: 10.1161/ATVBAHA.117.310605. Epub 2018 Feb 1. PMID: 29419407; PMCID: PMC5823793.

Hyngstrom AS, Murphy SA, Nguyen J, Schmit BD, Negro F, Gutterman DD, Durand MJ. . J Appl Physiol (1985). 2018 May 1;124(5):1140-1147. doi: 10.1152/japplphysiol.01072.2017. Epub 2018 Feb 8. PMID: 29420152; PMCID: PMC6050199.

Freed JK, Durand MJ. . Am J Physiol Heart Circ Physiol. 2018 Sep 1;315(3):H632-H633. doi: 10.1152/ajpheart.00313.2018. Epub 2018 Jun 15. PMID: 29906230.

Tinklenberg J, Beatka M, Bain JLW, Siebers EM, Meng H, Pearsall RS, Lawlor MW, Riley DA. . Muscle Nerve. 2018 Nov;58(5):718-725. doi: 10.1002/mus.26296. Epub 2018 Oct 2. PMID: 29981243; PMCID: PMC6246800.

Del Toro D, Nelson PA. . Phys Med Rehabil Clin N Am. 2018 Nov;29(4):783-792. doi: 10.1016/j.pmr.2018.06.012. Epub 2018 Sep 14. PMID: 30293631.

Connelly P, List C. . WMJ. 2018 Oct;117(4):164-166. PMID: 30407767.

Braza DW, Iverson M, Lee K, Hennessy C, Nelson D. . Prog Community Health Partnersh. 2018;12(2):165-172. doi: 10.1353/cpr.2018.0036. PMID: 30270226.

Murphy SA, Negro F, Farina D, Onushko T, Durand M, Hunter SK, Schmit BD, Hyngstrom A. . J Neurophysiol. 2018 Dec 1;120(6):3246-3256. doi: 10.1152/jn.00923.2017. Epub 2018 Oct 31. PMID: 30379629; PMCID: PMC6337044.

2017

Simpson DM, Patel AT, Alfaro A, Ayyoub Z, Charles D, Dashtipour K, Esquenazi A, Graham GD, McGuire JR, Odderson I. . PM R. 2017 Feb;9(2):136-148. doi: 10.1016/j.pmrj.2016.06.016. Epub 2016 Jun 23. PMID: 27346090.

Freed, J: Durand, M; Hoffmann, B; Densmore, J; Greene, A; Gutterman, D. . Am J Physiol Heart Circ Physiol. 2017 Feb 17.

Esquenazi A, Alfaro A, Ayyoub Z, Charles D, Dashtipour K, Graham GD, McGuire JR, Odderson IR, Patel AT, Simpson DM. . PM R. 2017 Mar 7.

Kaushal M, Oni-Orisan A, Chen G, Li W, Leschke J, Ward BD, Kalinosky B, Budde MD, Schmit BD, Li SJ, Muqeet V, Kurpad SN. . J Neurotrauma. 2017 Mar 15;34(6):1278-1282. doi: 10.1089/neu.2016.4649. Epub 2017 Jan 27. PMID: 27937140.

Wissel J, Bensmail D, Ferreira JJ, Molteni F, Satkunam L, Moraleda S, Rekand T, McGuire J, Scheschonka A, Flatau-Baqué B, Simon O, Rochford ET, Dressler D, Simpson DM; TOWER study investigators. . Neurology. 2017 Apr 4;88(14):1321-1328. doi: 10.1212/WNL.0000000000003789. Epub 2017 Mar 10. PMID: 28283596; PMCID: PMC5379931.

Buchanan CE, Kadlec AO, Hoch AZ, Gutterman DD, Durand MJ. . Med Sci Sports Exerc. 2017 Apr;49(4):669-675.

Nelson LD, Furger RE, Gikas P, Lerner EB, Barr WB, Hammeke TA, Randolph C, Guskiewicz K, McCrea MA. . J Int Neuropsychol Soc. 2017 Apr;23(4):293-303. doi: 10.1017/S1355617717000157. Epub 2017 Mar 27. PMID: 28343463; PMCID: PMC6637940.

Fritz JM, Inawat RR, Slavens BA, McGuire JR, Ziegler DW, Tarima SS, Grindel SI, Harris GF. . PM R. 2017 May;9(5):464-476. doi: 10.1016/j.pmrj.2016.08.031. Epub 2016 Sep 14. PMID: 27639653.

Mrotek LA, Bengtson M, Stoeckmann T, Botzer L, Ghez CP, McGuire J, Scheidt RA. . J Neuroeng Rehabil. 2017 Jun 28;14(1):64. doi: 10.1186/s12984-017-0269-3. PMID: 28659156; PMCID: PMC5490232.

Kadlec AO, Chabowski DS, Ait-Aissa K, Hockenberry JC, Otterson MF, Durand MJ, Freed JK, Beyer AM, Gutterman DD. . Hypertension. 2017 Jul;70(1):166-173. doi: 10.1161/HYPERTENSIONAHA.117.09289. Epub 2017 May 22. PMID: 28533333; PMCID: PMC5485836.

Kaushal M, Oni-Orisan A, Chen G, Li W, Leschke J, Ward D, Kalinosky B, Budde M, Schmit B, Li SJ, Muqeet V, Kurpad S. . 2017 Sep;7(7):413-423. doi: 10.1089/brain.2016.0468. Epub 2017 Aug 30. PMID: 28657334.

Lukaszewicz KM, Durand MJ, Priestley JRC, Schmidt JR, Allen LA, Geurts AM, Lombard JH. . J Vis Exp. 2017 Dec 5;(130):56133. doi: 10.3791/56133. PMID: 29286398; PMCID: PMC5755532.

2016

Belanger, HG; Powell-Cope, G; Spehar, AM; McCranie, M; Klanchar, SA; Yoash-Gantz, R; Kosasih, JB; Scholten, J. . J Rehabil Res Dev. 2016;53(6):767-780.

Beyer AM, Freed JK, Durand MJ, Riedel M, Ait-Aissa K, Green P, Hockenberry JC, Morgan RG, Donato AJ, Peleg R, Gasparri M, Rokkas CK, Santos JH, Priel E, Gutterman DD. . Circ Res. 2016 Mar 4;118(5):856-66.

Chen S, Andary M, Buschbacher R, Del Toro D, Smith B, So Y, Zimmermann K, Dillingham TR. . Muscle Nerve. 2016 Sep;54(3):371-7.

Dillingham T, Chen S, Andary M, Buschbacher R, Del Toro D, Smith B, Zimmermann K, So Y. . Muscle Nerve. 2016 Sep;54(3):366-70.

Durand MJ, Zinkevich NS, Riedel M, Gutterman DD, Nasci VL, Salato VK, Hijjawi JB, Reuben CF, North PE, Beyer AM. . Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1254-62.

Gutterman DD, Chabowski DS, Kadlec AO, Durand MJ, Freed JK, Ait-Aissa K, Beyer AM. . Circ Res. 2016 Jan 8;118(1):157-72.

Krajnak K, Raju SG, Miller GR, Johnson C, Waugh S, Kashon ML, Riley DA. . J Toxicol Environ Health A. 2016;79(3):101-11.

LaRoche AA, Nelson LD, Connelly PK, Walter KD, McCrea MA. . Clin J Sport Med 2016 Jan;26(1):33-9.

Research Committees and Affiliations

Research Administration Committee (PM&R)

Research Administration Committee (PM&R)

The RAC is composed of Department of Physical Medicine and Rehabilitation faculty. The RAC is under the direction of the Research Director. The department sets an annual budget to support research endeavors of faculty, fellows and residents. These funds will support pilot research proposals, attendance at national and regional meetings to present results of research and / or accept awards, and to provide assistance with publication costs.
Orthopedic Rehabilitation & Engineering Center (OREC)

Orthopedic Rehabilitation & Engineering Center (OREC)

The center was established in 1999 to facilitate research in support of the endeavors of the faculty, fellows, residents and graduate students participating in the programs of the ϰϲͼ Departments of Orthopaedic Surgery and Physical Medicine and Rehabilitation and of the MU School of Dentistry and the MU Department of Biomedical Engineering.

The center brings together common threads within the disciplines of engineering, biomedical sciences, materials sciences, and clinical dentistry. The result is a unique environment for interdisciplinary applied research.

Human Motion Analysis Laboratory (Gait Lab)

Human Motion Analysis Laboratory (Gait Lab)

The Department of Physical Medicine and Rehabilitation has collaborated with the Department of Orthopaedic Medicine and Marquette University to establish the Gait Lab. An agreement with the Gait Lab allows for the use of the facility without charge for resident research. Funded research budgets provide for financial support of the gait lab.
Rehabilitation Robotic Research and Design Lab (RRRD)

Rehabilitation Robotic Research and Design Lab (RRRD)

Established in 2004, the RRRD Lab is dedicated to the design, development and therapeutic use of novel, affordable, intelligent robotic / mechatronic and domotic assistants. It is affiliated with OREC and the Falk Neurorehabilitation Center at Marquette University.

The lab is focused on:

  • Examining underlying causes of upper limb impairment after neural disease, injury or cerebral accident.
  • Discovering effective methods to retrain functional recovery on daily living activities.
  • Developing new ways of facilitating independent living in daily living environments.

Contact Us

For more information on opportunities for collaboration, questions about research at the SRC, or questions on how to support research in PM&R please contact Dr. Matt Durand.

Dr. Matt Durand

mdurand@mcw.edu